Central African Rep.
Central Africa · Africa · Physician brief
Security situation — check travel advice before booking
The Central African Republic experiences armed conflict, banditry, and major restrictions on movement; medical and evacuation capacity is extremely limited. The Swiss FDFA advises against travel to most of the country. Consult current FDFA travel advice and arrange comprehensive evacuation insurance before any trip.
Swiss FDFA / EKRM ↗ · Updated 2026
Yellow fever vaccination certificate required for entry
The Central African Republic requires proof of yellow fever vaccination for all arriving travelers aged 9 months and older. Carry your International Certificate of Vaccination (yellow card). The vaccine must be given at least 10 days before arrival to be valid, and in Switzerland is only available at approved yellow-fever vaccination centres.
CDC / WHO IHR yellow fever requirements ↗ · Updated 2026
Meningitis belt — dry season risk
The Central African Republic sits in or adjacent to the African meningitis belt, where meningococcal disease risk rises during the dry season (roughly December to June). Meningococcal vaccination (ACWY) is recommended, especially for longer stays or close contact with the local population.
CDC / EKRM ↗ · Updated 2026
Vaccines
Disease-specific guidance
Malaria
HighHigh risk in all areas year-round, including the capital Bangui. P. falciparum predominates and is chloroquine-resistant. Continuous antimalarial chemoprophylaxis (atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine) is recommended for all travelers, combined with strict mosquito-bite prevention. Seek medical attention urgently for any fever during or up to a year after travel.
- Risk
- High, all areas, year-round
- Species
- Mainly P. falciparum
- Resistance
- Chloroquine-resistant
- Prevention
- Chemoprophylaxis + bite protection for all travelers
Yellow fever
HighThe Central African Republic is yellow-fever endemic and the vaccine is medically recommended for all travelers ≥9 months. A vaccination certificate is also REQUIRED for entry (all arrivals ≥9 months). Vaccinate at least 10 days before arrival; see the country alert above.
- Risk
- Endemic (vaccine recommended)
- Entry rule
- Certificate required, ≥9 months
- Timing
- ≥10 days before arrival
Dengue
LowDengue is present and transmitted by daytime-biting Aedes mosquitoes. Daytime mosquito-bite prevention (repellent, covering clothing) is the main protection; this also reduces other arboviral risks.
- Distribution
- Present countrywide
- Mosquito
- Aedes — bites during daytime
- Prevention
- Daytime bite protection
General prevention
Food & water
Strict food and water precautions are essential. Use bottled or treated water, avoid ice and raw produce, and eat only thoroughly cooked food. Healthcare access is severely limited — carry a personal medical kit and arrange evacuation insurance. Avoid wading or swimming in fresh water (schistosomiasis risk).
Mosquito protection
Aggressive mosquito-bite prevention is essential — chloroquine-resistant malaria risk is high year-round and country-wide, and antimalarial prophylaxis is recommended for all travelers. Dengue and tsetse-fly-borne sleeping sickness are also present. Use DEET or picaridin repellent, cover up, and sleep under an insecticide-treated net.
Sources
Based on CDC Travelers’ Health, CDC Yellow Book, and the Swiss Federal Vaccination Schedule (BAG). Always verify current recommendations before travel.
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This brief is for informational purposes and does not replace personalized medical advice.
Consult a travel medicine specialist 4–8 weeks before departure.