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eSwatini

Southern Africa · Africa · Physician brief

📝Draft — pending physician review
📝Draft — pending physician review. This brief was compiled from CDC, WHO, and EKRM/HealthyTravel sources (June 2026) and has not yet been verified by a clinician. Confirm specifics with a travel-medicine professional before relying on it.

Yellow fever certificate if arriving from a risk country

Eswatini has no domestic yellow fever transmission, so direct travel from Switzerland is not affected. However, a valid YF vaccination certificate is required for travelers aged 9 months and older arriving from (or having transited through) a country with risk of YF transmission — relevant for multi-country African itineraries.

CDC / WHO — Eswatini entry requirements ↗ · Updated 2026

Malaria

Moderate

Dengue

Low

Yellow fever

None

Chikungunya

None

Vaccines

VaccineRecommendationReference
Routine vaccines

Make sure you are up-to-date on all routine vaccines before every trip — per the Swiss BAG schedule. These include:

BAG Impfplan
Hepatitis A

Recommended for all travelers. Note for Swiss travelers: Hepatitis A is not part of the routine Swiss BAG childhood schedule, so most adult travelers will need vaccination.

CDC Yellow Book
Hepatitis B

Consider per individual risk and stay duration. Routine in the Swiss childhood schedule since 1998 — younger travelers are usually covered.

CDC Yellow Book
Rabies

Recommended for long stays, remote travel, cycling/motorbike trips, children, and those engaging in activities with potential animal or wildlife contact.

CDC Yellow Book
Typhoid

Recommended for most travelers, especially those visiting rural areas, staying with friends and relatives, or eating outside major hotels.

CDC Yellow Book

Disease-specific guidance

Malaria

Moderate

Seasonal risk (November–May) confined to the eastern lowveld bordering Mozambique and South Africa — the entire Lubombo region and the eastern halves of Hhohho, Manzini and Shiselweni (incl. Big Bend, Mhlume, Tshaneni). Chloroquine-resistant P. falciparum predominates; chemoprophylaxis is recommended for these areas in season. Western and central highlands (incl. Mbabane) are no-risk.

Risk area
Eastern lowveld (Lubombo; E. Hhohho/Manzini/Shiselweni)
Season
November–May
No risk
Western/central highlands incl. Mbabane
Species
P. falciparum (chloroquine-resistant)
Prophylaxis
Atovaquone-proguanil, doxycycline, or mefloquine

Yellow fever

None

No yellow fever risk in Eswatini. A YF certificate is required only for travelers ≥9 months arriving from a country with risk of YF transmission. Direct travel from Switzerland is not affected.

Status
No risk in country
Entry rule
Certificate only if arriving from a risk country

Dengue

Low

Sporadic dengue transmission can occur, carried by daytime-biting Aedes mosquitoes. Daytime bite-prevention measures reduce risk.

Mosquito
Aedes aegypti — bites during daytime
Prevention
Daytime repellent, covering clothing

General prevention

Food & water

Tap water in major hotels is generally safe; otherwise use bottled or treated water. Eat thoroughly cooked food and observe standard hygiene to reduce risk of traveler's diarrhea, hepatitis A, and typhoid.

Mosquito protection

Malaria risk is seasonal (November–May) in the eastern lowveld bordering Mozambique and South Africa — the Lubombo region and the eastern halves of Hhohho, Manzini, and Shiselweni (incl. Big Bend, Mhlume, Tshaneni). Use DEET- or picaridin-based repellent and long sleeves at dusk and dawn; consider chemoprophylaxis when visiting affected areas in season. Western and central highlands are no-risk.

Sources

Based on CDC Travelers’ Health, CDC Yellow Book, and the Swiss Federal Vaccination Schedule (BAG). Always verify current recommendations before travel.

Visiting more than one country?

Build a combined itinerary and get merged recommendations across all destinations.

Plan an itinerary

This brief is for informational purposes and does not replace personalized medical advice.
Consult a travel medicine specialist 4–8 weeks before departure.