São Tomé & Príncipe
Central Africa · Africa · Physician brief
Yellow fever — entry certificate if arriving from a risk country
There is no yellow fever risk in São Tomé & Príncipe, and the vaccine is generally not recommended for direct travel from Switzerland. However, a valid certificate is required for travelers aged 9 months and older arriving from (or transiting through) a yellow-fever-risk country — relevant if your itinerary includes mainland Central or West Africa.
CDC / WHO ↗ · Updated 2026
Vaccines
Disease-specific guidance
Malaria
ModeratePresent country-wide, year-round, though risk has fallen substantially after sustained elimination efforts. The predominant parasite is P. falciparum (with occasional P. malariae, P. ovale and P. vivax), and chloroquine resistance is documented. Discuss chemoprophylaxis versus standby treatment with your travel medicine specialist based on itinerary and current transmission levels.
- Risk
- Present country-wide, reduced but year-round
- Parasite
- Mainly P. falciparum
- Resistance
- Chloroquine-resistant
- Prevention
- Bite protection; prophylaxis or standby treatment per advice
Yellow fever
NoneNo yellow fever risk in country. The vaccine is generally not recommended for direct travel from Switzerland, but a valid certificate is required for travelers ≥9 months arriving from a yellow-fever-risk country. See country alert.
- Risk
- None in country
- Entry rule
- Certificate if arriving from risk country
General prevention
Food & water
Use bottled or reliably treated water, avoid ice and raw produce, and eat thoroughly cooked food. These measures reduce traveler's diarrhea, hepatitis A, and typhoid.
Mosquito protection
Mosquito-bite prevention is essential. Malaria risk has declined significantly thanks to sustained control efforts but remains present country-wide. Use DEET or picaridin repellent, cover up at dawn and dusk, and sleep under an insecticide-treated net.
Sources
Based on CDC Travelers’ Health, CDC Yellow Book, and the Swiss Federal Vaccination Schedule (BAG). Always verify current recommendations before travel.
Visiting more than one country?
Build a combined itinerary and get merged recommendations across all destinations.
This brief is for informational purposes and does not replace personalized medical advice.
Consult a travel medicine specialist 4–8 weeks before departure.