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São Tomé & Príncipe

Central Africa · Africa · Physician brief

📝Draft — pending physician review
📝Draft — pending physician review. This brief was compiled from CDC, WHO, and EKRM/HealthyTravel sources (June 2026) and has not yet been verified by a clinician. Confirm specifics with a travel-medicine professional before relying on it.

Yellow fever — entry certificate if arriving from a risk country

There is no yellow fever risk in São Tomé & Príncipe, and the vaccine is generally not recommended for direct travel from Switzerland. However, a valid certificate is required for travelers aged 9 months and older arriving from (or transiting through) a yellow-fever-risk country — relevant if your itinerary includes mainland Central or West Africa.

CDC / WHO · Updated 2026

Malaria

Moderate

Dengue

None

Yellow fever

None

Chikungunya

None

Vaccines

VaccineRecommendationReference
Routine vaccines

Make sure you are up-to-date on all routine vaccines before every trip — per the Swiss BAG schedule. These include:

BAG Impfplan
Hepatitis A

Recommended for all travelers to the region. Note for Swiss travelers: Hepatitis A is not part of the routine Swiss BAG childhood schedule, so most adult travelers will need vaccination.

CDC Yellow Book
Hepatitis B

Consider per individual risk and stay duration. Routine in Swiss childhood schedule since 1998 — younger travelers usually covered.

CDC Yellow Book
Rabies

Consider for longer stays, remote travel, work with animals, and for children. Rabid dogs are present and post-exposure care may be limited outside urban facilities.

CDC Yellow Book
Typhoid

Recommended for most travelers, especially those visiting rural areas or staying with friends and relatives.

CDC Yellow Book
Yellow fever

Not generally recommended for direct travel from Switzerland (no domestic risk), but a certificate is required if arriving from a yellow-fever-risk country. Single dose gives lifelong protection. See country alert.

CDC Yellow Book

Disease-specific guidance

Malaria

Moderate

Present country-wide, year-round, though risk has fallen substantially after sustained elimination efforts. The predominant parasite is P. falciparum (with occasional P. malariae, P. ovale and P. vivax), and chloroquine resistance is documented. Discuss chemoprophylaxis versus standby treatment with your travel medicine specialist based on itinerary and current transmission levels.

Risk
Present country-wide, reduced but year-round
Parasite
Mainly P. falciparum
Resistance
Chloroquine-resistant
Prevention
Bite protection; prophylaxis or standby treatment per advice

Yellow fever

None

No yellow fever risk in country. The vaccine is generally not recommended for direct travel from Switzerland, but a valid certificate is required for travelers ≥9 months arriving from a yellow-fever-risk country. See country alert.

Risk
None in country
Entry rule
Certificate if arriving from risk country

General prevention

Food & water

Use bottled or reliably treated water, avoid ice and raw produce, and eat thoroughly cooked food. These measures reduce traveler's diarrhea, hepatitis A, and typhoid.

Mosquito protection

Mosquito-bite prevention is essential. Malaria risk has declined significantly thanks to sustained control efforts but remains present country-wide. Use DEET or picaridin repellent, cover up at dawn and dusk, and sleep under an insecticide-treated net.

Sources

Based on CDC Travelers’ Health, CDC Yellow Book, and the Swiss Federal Vaccination Schedule (BAG). Always verify current recommendations before travel.

Visiting more than one country?

Build a combined itinerary and get merged recommendations across all destinations.

Plan an itinerary

This brief is for informational purposes and does not replace personalized medical advice.
Consult a travel medicine specialist 4–8 weeks before departure.