TravelMedEvidence. Expertise. Safer travel.
/
All countries
🇿🇲

Zambia

East Africa · Africa · Physician brief

📝Draft — pending physician review
📝Draft — pending physician review. This brief was compiled from CDC, WHO, and EKRM/HealthyTravel sources (June 2026) and has not yet been verified by a clinician. Confirm specifics with a travel-medicine professional before relying on it.

Schistosomiasis (bilharzia) in Lake Kariba and the Zambezi

Schistosomiasis (bilharzia) is present in Zambian freshwater, including Lake Kariba and the Zambezi River. Travelers are sometimes exposed during swimming, canoeing, or water sports. There is no vaccine and no reliable way to tell if water is safe. Avoid contact with untreated freshwater. The mist at Victoria Falls and chlorinated pools are not a schistosomiasis risk; the 'Devil's Pool' and swimming in the river are. Discuss screening and treatment (praziquantel) with your doctor if exposed.

CDC / WHO · Updated 2026

Yellow fever certificate only if arriving from a risk country

CDC does not consider Zambia a yellow fever risk country (vaccine not generally recommended, including for the Northwestern and Western Provinces), and the vaccine is not routinely recommended for travel from Switzerland. However, a YF vaccination certificate may be required if you are arriving from — or have recently transited — a country with yellow fever transmission risk. Direct travel from Switzerland is not affected.

WHO / Zambia entry requirements · Updated 2026

Malaria

High

Dengue

Low

Yellow fever

Moderate

Chikungunya

Low

Vaccines

VaccineRecommendationReference
Routine vaccines

Make sure you are up-to-date on all routine vaccines before every trip — per the Swiss BAG schedule. These include:

BAG Impfplan
Cholera

Consider for travelers to areas with active transmission, aid and healthcare workers, those staying in poor sanitary conditions, or with increased individual risk. No internal disease page — discuss with your travel clinic.

CDC Yellow Book
Hepatitis A

Recommended for all travelers to tropical and subtropical countries. Note for Swiss travelers: Hepatitis A is not part of the routine Swiss BAG childhood schedule, so most adult travelers will need vaccination.

CDC Yellow Book
Hepatitis B

Consider per individual risk and stay duration. Routine in the Swiss childhood schedule since 1998 — younger travelers usually covered.

CDC Yellow Book
Rabies

Particularly recommended for: long stays; high individual risk regardless of duration (cycling/motorbike trips, hiking and remote travel, small children, those working with animals, cavers — bats). Post-exposure care can be hard to obtain locally.

CDC Yellow Book
Typhoid

Recommended for most travelers, particularly those visiting rural areas, staying with friends and relatives, on longer trips, or in poor hygienic conditions.

CDC Yellow Book

Disease-specific guidance

Malaria

High

High risk year-round throughout the entire country, including the safari areas and the Victoria Falls / Livingstone region. P. falciparum (the most dangerous species) predominates and is chloroquine-resistant. Continuous chemoprophylaxis is recommended for essentially all travelers, in addition to strict mosquito-bite prevention.

Risk area
Entire country, year-round
Species
P. falciparum predominant
Resistance
Chloroquine-resistant
Prevention
Chemoprophylaxis (atovaquone-proguanil, doxycycline, or mefloquine) + bite protection

Yellow fever

Moderate

CDC does not classify Zambia as a yellow fever risk country, and the vaccine is not routinely recommended for travel from Switzerland. A YF certificate may be required only if you arrive from — or have recently transited — a country with yellow fever transmission risk (see country alert). Direct travel from Switzerland is not affected.

Risk
None per CDC — no domestic transmission
Vaccine
Not routinely recommended
Entry rule
Certificate only if arriving from a YF-risk country

Dengue

Low

Dengue transmission occurs and is mosquito-borne. The Aedes mosquito bites during the daytime, so day-time bite prevention complements the dusk-to-dawn protection used for malaria.

Distribution
Sporadic transmission
Mosquito
Aedes — bites during daytime
Prevention
Repellent and covering up by day

General prevention

Food & water

Use bottled or treated water, avoid ice from unverified sources, and eat thoroughly cooked food served hot. Strict food and water precautions reduce the risk of traveler's diarrhea, hepatitis A, typhoid, and cholera — particularly important outside well-run lodges.

Mosquito protection

Aggressive mosquito-bite prevention is essential — malaria is high risk year-round and country-wide. Use DEET or picaridin repellent, cover up at dusk and after dark, and sleep under an insecticide-treated net. Chemoprophylaxis is recommended for essentially all travelers.

Sources

Based on CDC Travelers’ Health, CDC Yellow Book, and the Swiss Federal Vaccination Schedule (BAG). Always verify current recommendations before travel.

Visiting more than one country?

Build a combined itinerary and get merged recommendations across all destinations.

Plan an itinerary

This brief is for informational purposes and does not replace personalized medical advice.
Consult a travel medicine specialist 4–8 weeks before departure.